Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/11089
Title: Premature circuit clotting due to likely mechanical failure during continuous renal replacement therapy.
Authors: Kim, In Byung;Fealy, Nigel;Baldwin, Ian;Bellomo, Rinaldo
Affiliation: Department of Intensive Care Medicine, Austin Hospital, Melbourne, Vic., Australia.
Issue Date: 22-Jul-2010
Citation: Blood Purification 2010; 30(2): 79-83
Abstract: Failure of extracorporeal circuit (EC) function during continuous renal replacement therapy (CRRT) appears most likely due to progressive circuit clotting or, in some cases, most likely due to mechanical problems that affect flow. We aimed to study the incidence of such likely mechanical circuit failure (MCF).Retrospective observational study in an adult ICU of a tertiary hospital.We studied 30 patients treated with CRRT via femoral vein vascular access. We obtained information on age, gender, diagnosis, mode of CRRT, circuit life, and blood chemistry. We defined MCF as 'likely' if there was a reduction of between 60 and 80% in circuit life compared to the previous or following circuit life and 'very likely' if such a reduction was between 81 and 100%.We studied 166 circuits in 30 different patients. Of these 26 were electively disconnected leaving 140 circuits with unplanned cessation of function. Among these circuits, likely MCF affected 10 circuits (7.1%) and very likely MCF affected 9 circuits (6.4%) for a total of 19 (13.6%) circuits.Mechanical circuit failure appears to affect approximately 1 in 8 circuits. Prospective studies are needed to understand why MCF occurs.
Internal ID Number: 20664199
URI: http://ahro.austin.org.au/austinjspui/handle/1/11089
DOI: 10.1159/000319001
URL: http://www.ncbi.nlm.nih.gov/pubmed/20664199
Type: Journal Article
Subjects: Aged
Blood Coagulation
Equipment Failure.statistics & numerical data
Female
Humans
Incidence
Intensive Care Units
Male
Middle Aged
Renal Replacement Therapy.instrumentation
Retrospective Studies
Appears in Collections:Journal articles

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