Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/11051
Title: Interpleural analgesia for attenuation of postoperative pain after hepatic resection.
Authors: Weinberg, Laurence;Scurrah, N;Parker, F;Story, David A;McNicol, Larry
Affiliation: Department of Surgery, University of Melbourne, Austin Hospital, Heidelberg, Victoria, Australia. Laurence.Weinberg@austin.org.au
Issue Date: 2-Jun-2010
Citation: Anaesthesia 2010; 65(7): 721-8
Abstract: We performed a prospective randomised trial to evaluate the analgesic efficacy of interpleural analgesia in patients undergoing hepatic resection. The control group (n = 25) received multimodal analgesia with intravenous morphine patient-controlled analgesia; in addition, the interventional group (n = 25) received interpleural analgesia with a 20-ml loading dose of levo bupivacaine 0.5% followed by a continuous infusion of levobupivacaine 0.125%. Outcome measures included pain intensity on movement using a visual analogue scale over 24 h, cumulative morphine and rescue analgesia requirements, patient satisfaction, hospital stay and all adverse events. Patients in the interpleural group were less sedated and none required treatment for respiratory depression compared to 6 (24%) in the control group (p< 0.01). Patients in the interpleural group also had lower pain scores during movement in the first 24 h. Patients' satisfaction, opioid requirements and duration of hospital stay were similar. We conclude that continuous interpleural analgesia augments intravenous morphine analgesia, decreases postoperative sedation and reduces respiratory depression after hepatic resection.
Internal ID Number: 20528839
URI: http://ahro.austin.org.au/austinjspui/handle/1/11051
DOI: 10.1111/j.1365-2044.2010.06384.x
URL: http://www.ncbi.nlm.nih.gov/pubmed/20528839
Type: Journal Article
Subjects: Adult
Aged
Aged, 80 and over
Analgesia, Patient-Controlled.methods
Analgesics, Opioid.administration & dosage
Anesthetics, Local.administration & dosage
Bupivacaine.administration & dosage
Drug Administration Schedule
Female
Hepatectomy.adverse effects.methods
Humans
Infusions, Parenteral
Male
Middle Aged
Morphine.administration & dosage
Pain Measurement.methods
Pain, Postoperative.etiology.prevention & control
Patient Satisfaction
Pleura
Prospective Studies
Young Adult
Appears in Collections:Journal articles

Files in This Item:
There are no files associated with this item.


Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.