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Title: Rapidly progressive glomerulonephritis complicating primary AL amyloidosis and multiple myeloma.
Authors: Crosthwaite, Amy;Skene, Alison;Mount, Peter
Affiliation: Department of Nephrology, Austin Health, Heidelberg, Victoria, Australia
Issue Date: 29-Dec-2009
Citation: Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association 2009; 25(8): 2786-9
Abstract: Crescentic glomerulonephritis is a rare complication of AA amyloidosis. There are no clinical case reports of this complicating AL amyloidosis. A 67-year-old man developed rapidly progressive glomerulonephritis (RPGN) on a background of primary AL amyloidosis and IgGkappa multiple myeloma. Investigations for causes of glomerulonephritis were negative, and a renal biopsy confirmed crescentic glomerulonephritis and amyloid deposition. He progressed to end stage kidney disease (ESKD) requiring dialysis after 2 months and died 7 months after diagnosis after further treatment of multiple myeloma failed to arrest progression. We believe this to be the first clinical case report of RPGN complicating primary (AL) renal amyloidosis and multiple myeloma.
Internal ID Number: 20042399
DOI: 10.1093/ndt/gfp715
Type: Journal Article
Subjects: Aged
Disease Progression
Fatal Outcome
Kidney Failure, Chronic.mortality.therapy
Multiple Myeloma.complications
Renal Dialysis
Appears in Collections:Journal articles

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