Please use this identifier to cite or link to this item:
https://ahro.austin.org.au/austinjspui/handle/1/10886
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Beart, P M | en |
dc.contributor.author | Lodge, D | en |
dc.date.accessioned | 2015-05-16T00:27:49Z | |
dc.date.available | 2015-05-16T00:27:49Z | |
dc.date.issued | 1990-05-01 | en |
dc.identifier.citation | The Journal of Pharmacy and Pharmacology; 42(5): 354-5 | en |
dc.identifier.govdoc | 1976785 | en |
dc.identifier.other | PUBMED | en |
dc.identifier.uri | https://ahro.austin.org.au/austinjspui/handle/1/10886 | en |
dc.description.abstract | Cortical slices removed from rats pre-treated with MK-901 0.5 mg kg-1 twice a day for 7 days had reduced responses to N-methyl-D-aspartate (NMDA) relative to quisqualate and glutamate compared with control animals. Potencies of competitive (CPMP) and non-competitive (ketamine) NMDA antagonists appeared unchanged. These changes are consistent with a reduced density of NMDA receptors. | en |
dc.language.iso | en | en |
dc.subject.other | Animals | en |
dc.subject.other | Binding, Competitive.drug effects | en |
dc.subject.other | Cerebral Cortex.drug effects.metabolism | en |
dc.subject.other | Dizocilpine Maleate.pharmacology | en |
dc.subject.other | Glutamates.pharmacology | en |
dc.subject.other | In Vitro Techniques | en |
dc.subject.other | Male | en |
dc.subject.other | N-Methylaspartate.pharmacology | en |
dc.subject.other | Quisqualic Acid.pharmacology | en |
dc.subject.other | Rats | en |
dc.subject.other | Rats, Inbred Strains | en |
dc.subject.other | Receptors, N-Methyl-D-Aspartate.metabolism | en |
dc.title | Chronic administration of MK-801 and the NMDA receptor: further evidence for reduced sensitivity of the primary acceptor site from studies with the cortical wedge preparation. | en |
dc.type | Journal Article | en |
dc.identifier.journaltitle | The Journal of pharmacy and pharmacology | en |
dc.identifier.affiliation | University of Melbourne, Austin Hospital, Heidelberg, Victoria, Australia | en |
dc.description.pages | 354-5 | en |
dc.relation.url | https://pubmed.ncbi.nlm.nih.gov/1976785 | en |
dc.type.austin | Journal Article | en |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
item.languageiso639-1 | en | - |
item.openairetype | Journal Article | - |
Appears in Collections: | Journal articles |
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