Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/10886
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dc.contributor.authorBeart, P Men
dc.contributor.authorLodge, Den
dc.date.accessioned2015-05-16T00:27:49Z
dc.date.available2015-05-16T00:27:49Z
dc.date.issued1990-05-01en
dc.identifier.citationThe Journal of Pharmacy and Pharmacology; 42(5): 354-5en
dc.identifier.govdoc1976785en
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/10886en
dc.description.abstractCortical slices removed from rats pre-treated with MK-901 0.5 mg kg-1 twice a day for 7 days had reduced responses to N-methyl-D-aspartate (NMDA) relative to quisqualate and glutamate compared with control animals. Potencies of competitive (CPMP) and non-competitive (ketamine) NMDA antagonists appeared unchanged. These changes are consistent with a reduced density of NMDA receptors.en
dc.language.isoenen
dc.subject.otherAnimalsen
dc.subject.otherBinding, Competitive.drug effectsen
dc.subject.otherCerebral Cortex.drug effects.metabolismen
dc.subject.otherDizocilpine Maleate.pharmacologyen
dc.subject.otherGlutamates.pharmacologyen
dc.subject.otherIn Vitro Techniquesen
dc.subject.otherMaleen
dc.subject.otherN-Methylaspartate.pharmacologyen
dc.subject.otherQuisqualic Acid.pharmacologyen
dc.subject.otherRatsen
dc.subject.otherRats, Inbred Strainsen
dc.subject.otherReceptors, N-Methyl-D-Aspartate.metabolismen
dc.titleChronic administration of MK-801 and the NMDA receptor: further evidence for reduced sensitivity of the primary acceptor site from studies with the cortical wedge preparation.en
dc.typeJournal Articleen
dc.identifier.journaltitleThe Journal of pharmacy and pharmacologyen
dc.identifier.affiliationUniversity of Melbourne, Austin Hospital, Heidelberg, Victoria, Australiaen
dc.description.pages354-5en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/1976785en
dc.type.austinJournal Articleen
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairetypeJournal Article-
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