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|Title:||Identification of four different CD46 (MCP) molecules with anti-peptide antibodies.|
|Authors:||Purcell, D F;Jonstone, R W;McKenzie, Ian F C|
|Affiliation:||Austin Research Institute, Austin Hospital, Heidelberg, Victoria, Australia.|
|Citation:||Biochemical and Biophysical Research Communications; 180(2): 1091-7|
|Abstract:||Four protein isoforms of the human CD46 molecule (MCP) have been identified using rabbit antisera against synthetic peptides corresponding to predicted cytoplasmic carboxyl-terminal sequences. Two different cytoplasmic tails, CD46 CYT 1 and CD46 CYT 2, were detected in CD46 molecules isolated from almost every cell type examined. Bands of 56 and 66 kDa were obtained from SDS-PAGE analyses of various cell types with both CYT 1 and CYT 2 antisera, which indicated that the size polymorphism of the CD46 molecule is not due to variations in the cytoplasmic tail and that each species contained two different sized molecules.|
|Internal ID Number:||1953714|
|Subjects:||Amino Acid Sequence|
Electrophoresis, Gel, Two-Dimensional
Electrophoresis, Polyacrylamide Gel
Enzyme-Linked Immunosorbent Assay
Molecular Sequence Data
|Appears in Collections:||Journal articles|
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