Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/10832
Title: Laboratory validation of the M-COVX metabolic module in measurement of oxygen uptake.
Authors: Stuart-Andrews, C R;Peyton, Philip J;Walker, T B;Cairncross, A D;Robinson, Gavin J B;Lithgow, B
Affiliation: Department of Anaesthesia, The Austin Hospital, Heidelberg, Victoria, Australia.
Issue Date: 1-May-2009
Citation: Anaesthesia and Intensive Care; 37(3): 399-406
Abstract: A practical method of breath-by-breath monitoring of metabolic gas exchange has previously been developed by GE Healthcare and can now be easily incorporated into existing anaesthetic and critical care monitoring (M-COVX). Previous research using this device has shown good accuracy and precision between the M-COVX measurements and a traditional measurement of gas uptake at the mouth and also against the reverse Fick method during cardiac surgery and critical care, but its accuracy in the paediatric situation and across a range of ventilatory settings awaits validation. We tested the M-COVX metabolic monitor in the laboratory comparing its measurement to a traditional Haldane transformation across a wide range of oxygen consumption values, from 50 ml/minute to just under 300 ml/minute, typical of those expected in anaesthetised adults and children. The M-COVX device showed acceptable accuracy with an overall mean bias of -3.3% (range -15.1 to +4.2%, P = 0.21). Excellent linearity was found, by y = 0.96x + 0.5 ml/minute, r = 0.99. The device showed acceptable robustness to ventilatory changes examined, including changes in respiratory rate, I:E ratio, FiO2 up to 75% and simulated spontaneous breathing. However any induced leak from around the simulated endotracheal tube caused a significant error in paediatric scenarios.
Internal ID Number: 19499859
URI: http://ahro.austin.org.au/austinjspui/handle/1/10832
URL: http://www.ncbi.nlm.nih.gov/pubmed/19499859
Type: Journal Article
Subjects: Adolescent
Adult
Age Factors
Anesthesia.methods
Child
Child, Preschool
Critical Care.methods
Equipment Design
Humans
Infant
Monitoring, Intraoperative.instrumentation
Monitoring, Physiologic.instrumentation
Oxygen Consumption
Pulmonary Gas Exchange
Reproducibility of Results
Respiration, Artificial.methods
Young Adult
Appears in Collections:Journal articles

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