Please use this identifier to cite or link to this item:
Title: Hashimoto encephalopathy and Down syndrome.
Authors: Brodtmann, Amy
Affiliation: National Stroke Research Institute, Level 1, Neurosciences Building, Austin Health, Heidelberg 3084, Australia.
Issue Date: 1-May-2009
Citation: Archives of Neurology; 66(5): 663-6
Abstract: Hashimoto encephalopathy is a potentially fatal condition associated with a presentation of myoclonus, altered conscious state, strokelike episodes, rapid cognitive decline, and neuropsychiatric symptoms. Both congenital hypothyroidism and acquired hypothyroidism are common in patients with Down syndrome.To describe the presentation of Hashimoto encephalopathy in patients with Down syndrome.Clinical case reports.General neurology unit. Patients Two Down syndrome patients diagnosed as having Hashimoto encephalopathy are described. Intervention High-dose oral corticosteroids.Neurologic examination, electroencephalography, and blood analysis results.Both patients responded to treatment, with a slow return to their premorbid level of function.Hashimoto encephalopathy should be considered in Down syndrome patients with rapidly progressive cognitive decline.
Internal ID Number: 19433669
DOI: 10.1001/archneurol.2009.45
Type: Journal Article
Subjects: Adrenal Cortex Hormones.administration & dosage
Brain Diseases, Metabolic.drug therapy.genetics.physiopathology
Disease Progression
Down Syndrome.drug therapy.genetics.physiopathology
Genetic Predisposition to Disease
Hashimoto Disease.drug therapy.genetics.physiopathology
Magnetic Resonance Imaging
Middle Aged
Thyroid Gland.physiopathology.secretion
Thyroid Hormones.metabolism.secretion
Treatment Outcome
Young Adult
Appears in Collections:Journal articles

Files in This Item:
There are no files associated with this item.

Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.