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|Title:||Scalp and limbic P3 event-related potentials in the assessment of patients with temporal lobe epilepsy.|
|Authors:||Puce, Aina;Bladin, Peter F|
|Affiliation:||Department of Neurology, University of Melbourne, Austin Hospital, Victoria, Australia.|
|Citation:||Epilepsia; 32(5): 629-34|
|Abstract:||Auditory oddball scalp and limbic P3s were recorded from 18 patients with unilateral temporal lobe epilepsy (TLE) prior to seizure surgery. Limbic P3s were unilaterally absent ipsilateral to the seizure focus and were present in the nonepileptogenic temporal lobe in all 18 cases studied. Scalp P3s, recorded from C3 and C4, on the other hand, were elicited bilaterally and there was no significant difference in amplitude or latency between the epileptogenic and nonepileptogenic sides. These data concur with studies of scalp P3 performed following surgery and suggest that the assessment of the contribution of limbic P3 to scalp P3 may be masked by volume conduction effects and other generators of P3. We conclude that the P3 recorded from central scalp sites, unlike its limbic counterpart, offers little clinical information in the presurgical assessment of patients with TLE.|
|Internal ID Number:||1915168|
Epilepsy, Temporal Lobe.diagnosis.physiopathology.surgery
|Appears in Collections:||Journal articles|
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