Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/10689
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dc.contributor.authorPuce, Ainaen
dc.contributor.authorAndrewes, D Gen
dc.contributor.authorBerkovic, Samuel Fen
dc.contributor.authorBladin, Peter Fen
dc.date.accessioned2015-05-16T00:13:20Z
dc.date.available2015-05-16T00:13:20Z
dc.date.issued1991-08-01en
dc.identifier.citationBrain : A Journal of Neurology; 114 ( Pt 4)(): 1647-66en
dc.identifier.govdoc1884171en
dc.identifier.otherPUBMEDen
dc.identifier.urihttp://ahro.austin.org.au/austinjspui/handle/1/10689en
dc.description.abstractA novel event-related potential (ERP) elicited by a visuospatial recognition memory task was recorded in 20 patients with temporal lobe epilepsy using depth electrodes sited in the temporal lobes. The ERPs comprised two components, an N400 and a P600, and were similar in morphology to the previously reported ERP to verbal recognition memory tasks. The two ERP components in both verbal and visuospatial tasks were dependent on stimulus type and our data suggest that they do not simply represent delayed P300 ERP responses. In 17/20 patients robust, reliable bilaterally present ERPs were elicited by both verbal and visuospatial memory tasks. N400 amplitude was larger in response to novel stimuli, whereas P600 amplitude was larger to repeated stimuli. P600 amplitude was larger in the right temporal lobe to both visuospatial and verbal stimulus material. N400 and P600 latencies did not vary with task, stimulus type or side of recording. In 3/20 patients, no ERPs were elicited by either memory task. In all 3 cases, unilateral temporal white matter abnormalities were demonstrated by magnetic resonance imaging. Behavioural measures, expressed in the form of standardized accuracy scores, did not differ from those of a normal control group, and hence are unlikely to account for the abnormalities in ERPs. These results are discussed with reference to the primate visual recognition memory pathway and suggest that ERPs to recognition memory tasks are generated by an interaction between the two homologous inferotemporal recognition memory pathways.en
dc.language.isoenen
dc.subject.otherAdulten
dc.subject.otherAnalysis of Varianceen
dc.subject.otherBehavioren
dc.subject.otherElectrophysiologyen
dc.subject.otherEpilepsy, Temporal Lobe.diagnosis.physiopathologyen
dc.subject.otherEvoked Potentials, Visual.physiologyen
dc.subject.otherFemaleen
dc.subject.otherHumansen
dc.subject.otherMagnetic Resonance Imagingen
dc.subject.otherMaleen
dc.subject.otherModels, Neurologicalen
dc.subject.otherNeuropsychological Testsen
dc.subject.otherPattern Recognition, Visual.physiologyen
dc.subject.otherSpace Perception.physiologyen
dc.subject.otherTemporal Lobe.pathology.physiologyen
dc.subject.otherVisual Perception.physiologyen
dc.titleVisual recognition memory. Neurophysiological evidence for the role of temporal white matter in man.en
dc.typeJournal Articleen
dc.identifier.journaltitleBrainen
dc.identifier.affiliationDepartment of Neurology, Austin Hospital, Heidelberg, Victoria, Australiaen
dc.description.pages1647-66en
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pubmed/1884171en
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