Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/10562
Title: Outcomes for general medical inpatients with diabetes mellitus and new hyperglycaemia.
Authors: Baker, Scott T;Chiang, Cherie Ying;Zajac, Jeffrey D;Bach, Leon A;Jerums, George;MacIsaac, Richard J
Affiliation: Austin Health and University of Melbourne, Melbourne, VIC, Australia. s.baker6@pgrad.unimelb.edu.au
Issue Date: 17-Mar-2008
Citation: Medical Journal of Australia; 188(6): 340-3
Abstract: To investigate the relationship between admission glycaemic status and inpatient mortality in patients with and without pre-existing diabetes.Prospective observational cohort study.A general medical ward in an Australian tertiary referral hospital.903 patients admitted to the general medical ward between February 2003 and July 2004.Inpatient death.The overall inpatient mortality was 5.4% (n = 49). In the total cohort, age > 75 years and admission fasting plasma glucose (FPG) levels > or = 5.6 mmol/L were independent predictors of mortality. For patients without a known history of diabetes, each 1 mmol/L rise in admission FPG was associated with a 33% increase in mortality. In these patients, elevated (> 6.0%) and normal glycated haemoglobin (HbA(1c)) levels were associated with mortalities of 11.3% and 4.4%, respectively (odds ratio, 2.47; 95% CI, 1.16-5.26). In contrast, in patients with known diabetes, there was no association between admission FPG levels, HbA(1c) and mortality. Length of stay was not independently associated with FPG, HbA(1c), or diabetes status.In patients without known diabetes, the risk of death was increased for admission FPG levels > or = 5.6 mmol/L. However, pre-existing abnormal glucose metabolism, reflected by elevated HbA(1c) levels, appeared a more important predictor of inpatient mortality than glucose levels in patients without known diabetes.
Internal ID Number: 18341457
URI: http://ahro.austin.org.au/austinjspui/handle/1/10562
URL: http://www.ncbi.nlm.nih.gov/pubmed/18341457
Type: Journal Article
Subjects: Aged
Aged, 80 and over
Australia.epidemiology
Diabetes Complications
Diagnostic Tests, Routine
Female
Hemoglobin A, Glycosylated.analysis
Humans
Hyperglycemia.complications.mortality
Inpatients
Male
Prospective Studies
Appears in Collections:Journal articles

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