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|Title:||Mycobacterium ulcerans in mosquitoes captured during outbreak of Buruli ulcer, southeastern Australia.|
|Authors:||Johnson, Paul D R;Azuolas, Joseph;Lavender, Caroline J;Wishart, Elwyn;Stinear, Timothy P;Hayman, John A;Brown, Lynne;Jenkin, Grant A;Fyfe, Janet A M|
|Affiliation:||Infectious Disease Department, Austin Health, Melbourne, Victoria, Australia. firstname.lastname@example.org|
|Citation:||Emerging Infectious Diseases; 13(11): 1653-60|
|Abstract:||Buruli ulcer (BU) occurs in >30 countries. The causative organism, Mycobacterium ulcerans, is acquired from the environment, but the exact mode of transmission is unknown. We investigated an outbreak of BU in a small coastal town in southeastern Australia and screened by PCR mosquitoes caught there. All cases of BU were confirmed by culture or PCR. Mosquitoes were trapped in multiple locations during a 26-month period. BU developed in 48 residents of Point Lonsdale/Queenscliff and 31 visitors from January 2001 through April 2007. We tested 11,504 mosquitoes trapped at Point Lonsdale (predominantly Aedes camptorhynchus). Forty-eight pools (5 species) were positive for insertion sequence IS2404 (maximum likelihood estimate 4.3/1,000), and we confirmed the presence of M. ulcerans in a subset of pools by detection of 3 additional PCR targets.|
|Internal ID Number:||18217547|
Aged, 80 and over
Communicable Diseases, Emerging.epidemiology.microbiology
Mycobacterium ulcerans.genetics.isolation & purification
Polymerase Chain Reaction.methods
|Appears in Collections:||Journal articles|
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