Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/10434
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dc.contributor.authorMcMahon, James Hen
dc.contributor.authorO'keeffe, Jason Men
dc.contributor.authorGrayson, M Lindsayen
dc.date.accessioned2015-05-15T23:52:54Z
dc.date.available2015-05-15T23:52:54Z
dc.date.issued2007-08-03en
dc.identifier.citationScandinavian Journal of Infectious Diseases 2007; 40(1): 40-3en
dc.identifier.govdoc17852904en
dc.identifier.otherPUBMEDen
dc.identifier.urihttp://ahro.austin.org.au/austinjspui/handle/1/10434en
dc.description.abstractAlthough serious infections such as bacterial endocarditis (BE) are being increasingly treated with parenteral antibiotics via Hospital-in-the-Home (HITH) programmes in Australia, there are few published data to confirm the safety and efficacy of this treatment modality, especially among patients with BE due to pathogens other than streptococci. In a 12-month prospective, multi-site study we assessed HITH treatment outcomes for all cases of BE. Among the 40 BE cases (29 'definite', 11 'possible'; Duke criteria) caused by a range of pathogens (16 staphylococci spp., 11 streptococci, 4 other, 9 culture-negative), cure was achieved in 37 (93%) cases. BE due to Staphylococcus aureus was significantly associated with an inferior outcome (p =0.046). Adverse events were relatively common (9/40), but most were not severe and were managed with continuation of HITH care. BE can be safely managed via HITH, but particular care in patient selection is necessary, especially for cases due to S. aureus.en
dc.language.isoenen
dc.subject.otherAdulten
dc.subject.otherAgeden
dc.subject.otherAnti-Bacterial Agents.therapeutic useen
dc.subject.otherAustraliaen
dc.subject.otherEndocarditis, Bacterial.drug therapyen
dc.subject.otherFemaleen
dc.subject.otherHome Care Servicesen
dc.subject.otherHumansen
dc.subject.otherMaleen
dc.subject.otherMiddle Ageden
dc.subject.otherPatient Selectionen
dc.subject.otherPilot Projectsen
dc.subject.otherProspective Studiesen
dc.titleIs hospital-in-the-home (HITH) treatment of bacterial endocarditis safe and effective?en
dc.typeJournal Articleen
dc.identifier.journaltitleScandinavian journal of infectious diseasesen
dc.identifier.affiliationjhmcmahon@yahoo.comen
dc.identifier.affiliationInfectious Diseases Department, Austin Health, Heidelberg, Victoria, Australiaen
dc.identifier.doi10.1080/00365540701522942en
dc.description.pages40-3en
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pubmed/17852904en
dc.contributor.corpauthorVictorian Hith Outcomes Study Groupen
Appears in Collections:Journal articles

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