Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/10431
Title: The role of abdominal resectional surgery in metastatic melanoma.
Authors: Hodgson, Russell;Fink, Michael A;Jones, Robert M
Affiliation: Department of Surgery, University of Melburn, Austin Health, Melbourne, Victoria, Australia. russell.hodgson@gmail.com
Issue Date: 1-Oct-2007
Citation: Anz Journal of Surgery; 77(10): 855-9
Abstract: We reviewed our experience to determine the role of resectional surgery in metastatic melanoma to the abdomen.An observational study of 25 patients at the Austin Hospital, Melbourne from 1997 to 2005.The median survival after abdominal resectional surgery was 8.3 (range 0.4-41.1) months. Fourteen patients who underwent resection with curative intent (extra-abdominal disease controlled and complete macroscopic clearance of abdominal disease) had improved survival compared with 11 patients who underwent palliative resection (12 month survival, 89 vs 10%, respectively, P < 0.0001). Survival was also superior in patients with up to two metastases compared with more than two (P = 0.0001) and in patients with serum albumin of at least 35 g/L (P = 0.0031). Intent of surgery (curative vs palliative) was the only factor significant on multivariate analysis (P = 0.001). Of patients with preoperative symptoms, 87% had resolution of these symptoms. Operative morbidity was 12%, and 30-day mortality was 4%.In a highly selected group of patients with intra-abdominal melanoma metastases, resection of intra-abdominal metastases with curative intent resulted in prolonged survival compared with patients who underwent palliative resection. Those who underwent palliative resection had good relief of symptoms with minimal morbidity.
Internal ID Number: 17803548
URI: http://ahro.austin.org.au/austinjspui/handle/1/10431
DOI: 10.1111/j.1445-2197.2007.04258.x
URL: http://www.ncbi.nlm.nih.gov/pubmed/17803548
Type: Journal Article
Subjects: Abdominal Neoplasms.pathology.surgery
Adult
Aged
Aged, 80 and over
Female
Follow-Up Studies
Humans
Male
Melanoma.mortality.pathology.surgery
Middle Aged
Neoplasm Metastasis
Regression Analysis
Retrospective Studies
Survival Analysis
Time Factors
Appears in Collections:Journal articles

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