Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/10341
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dc.contributor.authorBaldwin, Ianen
dc.contributor.authorNaka, Toshioen
dc.contributor.authorKoch, Billen
dc.contributor.authorFealy, Nigelen
dc.contributor.authorBellomo, Rinaldoen
dc.date.accessioned2015-05-15T23:45:51Z-
dc.date.available2015-05-15T23:45:51Z-
dc.date.issued2007-03-24en
dc.identifier.citationIntensive Care Medicine 2007; 33(5): 830-5en
dc.identifier.govdoc17384931en
dc.identifier.otherPUBMEDen
dc.identifier.urihttp://ahro.austin.org.au/austinjspui/handle/1/10341en
dc.description.abstractContinuous veno-venous haemofiltration (CVVH) is an established treatment for acute renal failure (ARF). Recently, extended intermittent dialytic techniques have been proposed for the treatment of ARF. The aim of this study was to compare these two approaches.Intensive care unit of tertiary hospital.Sixteen critically ill patients with ARF.Randomised controlled trial.We randomised sixteen patients to three consecutive days of treatment with either CVVH (8) or extended daily dialysis with filtration (EDDf) (8) and compared small-solute, electrolyte and acid-base control.There was no significant difference between the two therapies for urea or creatinine levels over 3 days. Of 80 electrolyte measurements taken before treatment, 19 were abnormal. All values were corrected as a result of treatment, except for one patient in the CVVH group who developed hypophosphataemia (0.54 mmol/l) at 72 h. After 3 days of treatment, there was a mild but persistent metabolic acidosis in the EDDf group compared to the CVVH group (median bicarbonate: 20 mmol/l vs. 29 mmol/l: p=0.039; median base deficit: -4 mEq/l vs. -2.1 mEq/l, p=0.033).CVVH and EDDf as prescribed achieved similar control of urea, creatinine and electrolytes. Acidosis was better controlled with CVVH.en
dc.language.isoenen
dc.subject.otherAPACHEen
dc.subject.otherAcid-Base Equilibriumen
dc.subject.otherAcute Kidney Injury.blood.therapyen
dc.subject.otherAgeden
dc.subject.otherFemaleen
dc.subject.otherHemofiltration.methodsen
dc.subject.otherHumansen
dc.subject.otherIntensive Careen
dc.subject.otherMaleen
dc.subject.otherMiddle Ageden
dc.subject.otherPilot Projectsen
dc.subject.otherRenal Dialysis.methodsen
dc.titleA pilot randomised controlled comparison of continuous veno-venous haemofiltration and extended daily dialysis with filtration: effect on small solutes and acid-base balance.en
dc.typeJournal Articleen
dc.identifier.journaltitleIntensive care medicineen
dc.identifier.affiliationDepartment of Intensive Care, Austin Health, Heidelberg, Victoria, Australiaen
dc.identifier.doi10.1007/s00134-007-0596-0en
dc.description.pages830-5en
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pubmed/17384931en
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