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|Title:||Post-ictal recognition memory predicts laterality of temporal lobe seizure focus: comparison with post-operative data.|
|Authors:||Andrewes, D G;Puce, Aina;Bladin, Peter F|
|Affiliation:||Department of Neuropsychology, Austin Hospital, Heidelberg, Victoria, Australia|
|Citation:||Neuropsychologia; 28(9): 957-67|
|Abstract:||Standardized verbal and visuo-spatial memory recognition were obtained on 15 patients with unilateral temporal lobe epilepsy (TLE), using a reference group of 43 (12 males, 31 females) subjects with no previous history of neurological disease. Inter-ictal measures on these two tasks failed to differentiate between those patients with left vs right seizure foci. When eight of these patients were tested post-ictally (within 1 hr of seizure), seven showed the expected selective memory impairment when compared to inter-ictal performance. Left TLE patients showed a relative lowering of verbal memory, whereas patients with right TLE showed a relative visuo-spatial memory impairment. A similar result was also found in the patients when a comparison between pre-operative (inter-ictal) and post-operative performance was made, thereby further substantiating the validity of the tasks. This significant association between side of seizure focus and selective impairment of post-ictal memory performance provides evidence of a more direct method of neuropsychological diagnosis in TLE patients prior to surgery.|
|Internal ID Number:||1701863|
Brain Damage, Chronic.physiopathology
Epilepsy, Temporal Lobe.physiopathology.surgery
Pattern Recognition, Visual.physiology
|Appears in Collections:||Journal articles|
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