Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/10217
Title: Postoperative changes in prothrombin time following hepatic resection: implications for perioperative analgesia.
Authors: Weinberg, Laurence;Scurrah, N;Gunning, K;McNicol, Larry
Affiliation: Department of Anaesthesia, Austin Health, Victoria, Australia.
Issue Date: 1-Aug-2006
Citation: Anaesthesia and Intensive Care; 34(4): 438-43
Abstract: Disorders of coagulation may occur after uncomplicated hepatic resection in patients who have normal preoperative coagulation profiles and liver function tests. We present a retrospective study performed in a tertiary care university teaching hospital examining changes in liver function tests and coagulation profiles in patients undergoing hepatic resection. Data were obtained for 124 patients. When compared to the preoperative values, prothrombin times were significantly increased throughout the postoperative period. Prolongation of the prothrombin time was related to both duration of surgery and hepatic resection weight. There was no relationship between prothrombin time and patient age. Disorders of coagulation occur after hepatic resection even in patients who have normal preoperative coagulation and liver function tests. This has implications for anaesthetic practice, particularly when considering the use of an indwelling epidural catheter in patients undergoing hepatic resection.
Internal ID Number: 16913338
URI: http://ahro.austin.org.au/austinjspui/handle/1/10217
URL: http://www.ncbi.nlm.nih.gov/pubmed/16913338
Type: Journal Article
Subjects: Analgesia
Anesthesia, General
Blood Coagulation Disorders.epidemiology.etiology
Female
Humans
Liver.surgery
Liver Function Tests
Male
Middle Aged
Pain, Postoperative.drug therapy
Postoperative Complications.blood.epidemiology
Prothrombin Time
Retrospective Studies
Appears in Collections:Journal articles

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