Please use this identifier to cite or link to this item:
|Title:||Serotonergic effects of isatin: an endogenous MAO inhibitor related to tribulin.|
|Authors:||McIntyre, I M;Norman, Trevor R|
|Affiliation:||Department of Psychiatry, University of Melbourne, Austin Hospital, Heidelberg, Victoria, Australia.|
|Citation:||Journal of Neural Transmission. General Section; 79(1-2): 35-40|
|Abstract:||A study of the acute effects of isatin, an endogenous MAO inhibitor related to tribulin, on rat brain serotonergic function was undertaken. A single dose of isatin significantly increased 5-HT concentrations in the hypothalamus and cortex but did not significantly alter 5-HIAA concentrations. Synaptosomal 5-HT uptake was unaffected but there was a trend for the number of 3H-ketanserin binding sites was to be decreased. The results of the study are discussed in terms of the relationship of isatin to tribulin and their possible causal role in stress.|
|Internal ID Number:||1688707|
Cerebral Cortex.drug effects.metabolism
Monoamine Oxidase Inhibitors.metabolism.pharmacology
Rats, Inbred Strains
|Appears in Collections:||Journal articles|
Files in This Item:
There are no files associated with this item.
Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.